Immunization Grade Rat Type II Collagen, 2 mg/ml x 2.5 ml
R. B. Clague, K. Morgan, T. I. Reynolds, H. J. Williams. The prevalence of serum IgG antibodies to Type II Collagen in American patients with rheumatoid arthritis. British Journal of Rheumatology, 1994;33:336338 Kim W.U., Yoo W.H., Won Park, Kang Y.M., Kim S.I., Park J.H., Lee S.S., Joo Y.S, Min J. K., Hong Y.S., Lee S.H., Park S.H., Cho C.S., Kim H.Y. IgG antibodies to type II collagen reflect inflammatory activity in patients with rheumatoid arthritis. Journal of Rheumatology, 2000; 27(3):575581. Terato K., DeArmey D.A., Ye X.J., Griffiths M.M., Cremer M.A. The Mechanism of Autoantibody Formation to Cartilage in Rheumatoid Arthritis: Possible CrossReaction of Antibodies to Dietary Collagens with Autologous Type II Collagen. Clin Imm Immunopath, 1996; 79(2):142154(13) Terato K, Shimozuru Y, Katayama K, et al. Specificity of antibodies to type II collagen in rheumatoid arthritis. Arthritis Rheum 1990;33:1493500.
Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
Collagen Types in bones and muscles can be hydrolyzed and used in human grafts. ( Type II )